Published April 2008 | Version v1
Journal article Metadata-only

Microsynthesis of insecticidal component 6β-propoxycelangulin V

Creators

  • 1. Shanghai Inst. of Organic Chemistry, Chinese Academy of Sciences, Shanghai (China)
  • 2. Institute of Pesticide, Northwest Univ. of Agriculture and Forestry, Shaanxi, Yangling (China)
  • 3. Institute of Nuclear-Agricultural Science, Zhejiang Univ., Hangzhou (China)

Description

An insecticidal compound 6β-propoxycelangulin V was synthesized from celangulin V and 1-propanol through anhydrous iodination and Williamson reactions. The purpose of the study was to develop the microsynthetic method of 6β- propoxycelangulin V. The powdered root bark of Chinese bittersweet (Celastrus angulatus Max.) was extracted by benzene under reflux, followed by purification by macroporous-resin and silica-gel chromatography. The desired product was purified by RP-HPLC and identified by HRMS, 1H NMR and 13C NMR. The total yield was about 17%, and the purity was higher than 98%. This method could be applied in radiosythesis of 6β-([1-14C]propoxy)celangulin V. (authors)

Additional details

Publishing Information

Journal Title
Acta Agriculturae Nucleatae Sinica
Journal Volume
22
Journal Issue
2
Journal Page Range
p. 223-227
ISSN
1000-8551

INIS

Country of Publication
China
Country of Input or Organization
China
INIS RN
41122555
Subject category
S38: RADIATION CHEMISTRY, RADIOCHEMISTRY AND NUCLEAR CHEMISTRY;
Descriptors DEI
BARK; BENZENE; CARBON 13; CARBON 14; CHEMICAL PREPARATION; CHEMICAL REACTION YIELD; CHINA; HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROGEN 1; IMPURITIES; INSECTICIDES; IODINATION; LABELLED COMPOUNDS; LABELLING; NUCLEAR MAGNETIC RESONANCE; PROPANOLS; PURIFICATION; RESINS; ROOTS
Descriptors DEC
ALCOHOLS; AROMATICS; ASIA; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; CARBON ISOTOPES; CHEMICAL REACTIONS; CHROMATOGRAPHY; EVEN-EVEN NUCLEI; EVEN-ODD NUCLEI; HALOGENATION; HYDROCARBONS; HYDROGEN ISOTOPES; HYDROXY COMPOUNDS; ISOTOPES; LIGHT NUCLEI; LIQUID COLUMN CHROMATOGRAPHY; MAGNETIC RESONANCE; NUCLEI; ODD-EVEN NUCLEI; ORGANIC COMPOUNDS; ORGANIC POLYMERS; PESTICIDES; PETROCHEMICALS; PETROLEUM PRODUCTS; PLANT TISSUES; POLYMERS; RADIOISOTOPES; RESONANCE; SEPARATION PROCESSES; STABLE ISOTOPES; SYNTHESIS; YEARS LIVING RADIOISOTOPES; YIELDS

Optional Information

Notes
3 figs., 19 refs.