Published May 2015 | Version v1
Journal article Metadata-only

Gadolinia nanofibers as a multimodal bioimaging and potential radiation therapy agent

Creators

  • 1. Petrozavodsk State University, 185910 Petrozavodsk, Karelian Republic (Russian Federation)
  • 2. INMATECH Intelligent Materials Technology, SE-127 45 Skärholmen (Sweden)
  • 3. KTH Royal Institute of Technology, SE-164 40 Stockholm-Kista (Sweden)
  • 4. Racah Institute of Physics, Hebrew University of Jerusalem, 91904 Jerusalem (Israel)

Description

Continuous bead-free C-type cubic gadolinium oxide (Gd2O3) nanofibers 20-30 μm long and 40-100 nm in diameter were sintered by sol-gel calcination assisted electrospinning technique. Dipole-dipole interaction of neighboring Gd3+ ions in nanofibers with large length-to-diameter aspect ratio results in some kind of superparamagnetic behavior: fibers are magnetized twice stronger than Gd2O3 powder. Being compared with commercial Gd-DTPA/Magnevist®, Gd2O3 diethyleneglycol-coated (Gd2O3-DEG) fibers show high 1/T1 and 1/T2 proton relaxivities. Intense room temperature photoluminescence, high NMR relaxivity and high neutron scattering cross-section of 157Gd nucleus promise to integrate Gd2O3 fibers for multimodal bioimaging and neutron capture therapy

Additional details

Identifiers

DOI
10.1063/1.4919810;

Publishing Information

Journal Title
AIP Advances
Journal Volume
5
Journal Issue
5
Journal Page Range
p. 057104-057104.9
ISSN
2158-3226
CODEN
AAIDBI

INIS

Country of Publication
United States
Country of Input or Organization
International Atomic Energy Agency (IAEA)
INIS RN
47058623
Subject category
S36: MATERIALS SCIENCE; S77: NANOSCIENCE AND NANOTECHNOLOGY;
Descriptors DEI
ASPECT RATIO; CALCINATION; COMPARATIVE EVALUATIONS; CROSS SECTIONS; DIPOLES; FIBERS; GADOLINIUM 157; GADOLINIUM IONS; GADOLINIUM OXIDES; INTERACTIONS; NANOFIBERS; NEUTRON CAPTURE THERAPY; NEUTRON DIFFRACTION; NUCLEAR MAGNETIC RESONANCE; PHOTOLUMINESCENCE; POWDERS; PROTONS; SOL-GEL PROCESS; SUPERPARAMAGNETISM
Descriptors DEC
BARYONS; CHALCOGENIDES; CHARGED PARTICLES; CHEMICAL REACTIONS; COHERENT SCATTERING; DECOMPOSITION; DIFFRACTION; DIMENSIONLESS NUMBERS; ELEMENTARY PARTICLES; EMISSION; EVALUATION; EVEN-ODD NUCLEI; FERMIONS; GADOLINIUM COMPOUNDS; GADOLINIUM ISOTOPES; HADRONS; INTERMEDIATE MASS NUCLEI; IONS; ISOTOPES; LUMINESCENCE; MAGNETIC RESONANCE; MAGNETISM; MEDICINE; MULTIPOLES; NANOSTRUCTURES; NEUTRON THERAPY; NUCLEAR MEDICINE; NUCLEI; NUCLEONS; OXIDES; OXYGEN COMPOUNDS; PHOTON EMISSION; PYROLYSIS; RADIOLOGY; RADIOTHERAPY; RARE EARTH COMPOUNDS; RARE EARTH NUCLEI; RESONANCE; SCATTERING; STABLE ISOTOPES; THERAPY; THERMOCHEMICAL PROCESSES

Optional Information

Notes
(c) 2015 Author(s)