Researches on the Improvement of the Bioactivity of TiO₂ Deposits, Obtained by Magnetron Sputtering - DC

In this paper, layers of TiO₂ were deposited, by magnetron sputtering, on a glass support. The parameters of the deposition process were kept constant except for the O₂/(Ar + O2) ratio that varied on three levels. The physical and mechanical properties of the layers obtained were investigated by SEM optical microscopy, electronics, AFM and X-ray diffraction. The bioactivity of TiO₂ surfaces was investigated by growing M3C3-E1 osteoblast cells produced by RIKEN Cell Bank (Japan) for a period of 5 days. The modification of the working environment in the enclosure determines both the phasic modification in the TiO₂ film, respectively the amount of the anatase or rutile phase and the decrease of the average roughness of the film from 112.3nm to 56.7nm. The research has demonstrated that the finer layers with a high content of anatase promote the growth of M3C3-E1 cells. (paper)