Published September 1983
| Version v1
Journal article
Karyotypic findings in a case of prolymphocytic leukemia with a history of radiation exposure
Creators
- 1. Roswell Park Memorial Institute, Buffalo, New York
Description
Cytogenetic examination, utilizing B- and T-cell mitogens, of the peripheral blood lymphocytes of a patient with the prolymphocytic variant of chronic lymphocytic leukemia (CLL) and a history of radiation exposure revealed two abnormal clones. One clone with 48 chromosomes (+t(6;12),6q-, +12,14q+) may be derived from CLL cells, whereas the clone with 46 chromosomes and a ring number 11 possibly originated from normal T and/or B cells affected by past irradiation
Additional details
Publishing Information
- Journal Title
- Cancer Genet. Cytogenet.
- Journal Volume
- 10
- Journal Issue
- 1
- Series
- Cancer Genet. Cytogenet.
- Journal Page Range
- 79-85
- ISSN
- 0165-4608
INIS
- Country of Publication
- United States
- Country of Input or Organization
- United States
- INIS RN
- 15021124
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Descriptors DEI
- CHROMOSOMAL ABERRATIONS; DELAYED RADIATION EFFECTS; KARYOTYPE; LEUKEMIA; LYMPHOCYTES; MITOGENS; ONCOGENIC VIRUSES; PATIENTS; RADIATION EFFECTS
- Descriptors DEC
- ANIMAL CELLS; BIOLOGICAL EFFECTS; BIOLOGICAL MATERIALS; BIOLOGICAL RADIATION EFFECTS; BLOOD; BLOOD CELLS; BODY FLUIDS; CONNECTIVE TISSUE CELLS; DISEASES; HEMIC DISEASES; LEUKOCYTES; MATERIALS; MICROORGANISMS; MUTATIONS; NEOPLASMS; PARASITES; SOMATIC CELLS; VIRUSES