Published 1990 | Version v1
Report Metadata-only

Comparative effects of neutron and gamma irradiation on striatal D1 and D2 dopamine receptors in rats

Creators

  • 1. Centre de Recherche du Service de Sante des Armees, 38 - La Tronche (France)

Description

D1 and D2 receptors densities and activities were studied in the striatum in rats irradiated with 1 MeV fission neutrons or exposed to 60Co gamma-rays at the dose of 7 Gy. No modulation of Dopamine receptors was observed after gamma irradiation. In constrast neutron irradiation induces, specifically, an increase of D1-receptor density in the striatum while the D2-receptor density and affinity were unchanged

Abstract (French)

Les effets d'une irradiation en fluence mixte (neutron/gamma) sur les recepteurs D1 et D2 ont ete compares a ceux induits par une irradiation gamma a la meme dose (7 Gy H + 1,5). L'irradiation neutronique induit de facon specifique une augmentation de la densite en recepteurs D1
Part of:
Scientific works 1989. Centre de Recherches du Service de Sante des Armees

Additional details

Additional titles

Original title (French)
Effets compares de l'irradiation gamma et de l'irradiation neutronique sur les recepteurs dopaminergiques du striatum de rat

Publishing Information

Imprint Title
Scientific works 1989. Centre de Recherches du Service de Sante des Armees
Imprint Pagination
353 p.
Journal Page Range
p. 19-20.
Report number
SSA--1990-TS-11

INIS

Country of Publication
France
Country of Input or Organization
France
INIS RN
22050662
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
Descriptors DEI
BIOLOGICAL RADIATION EFFECTS; BRAIN; COMPARATIVE EVALUATIONS; DOPAMINE; GAMMA RADIATION; NEUTRONS; RATS; RECEPTORS
Descriptors DEC
AMINES; ANIMALS; AROMATICS; AUTONOMIC NERVOUS SYSTEM AGENT; BARYONS; BIOLOGICAL EFFECTS; BODY; CARDIOTONICS; CARDIOVASCULAR AGENTS; CENTRAL NERVOUS SYSTEM; DRUGS; ELECTROMAGNETIC RADIATION; ELEMENTARY PARTICLES; EVALUATION; FERMIONS; HADRONS; HYDROXY COMPOUNDS; IONIZING RADIATIONS; MAMMALS; NERVOUS SYSTEM; NEUROREGULATORS; NUCLEONS; ORGANIC COMPOUNDS; ORGANS; PHENOLS; POLYPHENOLS; RADIATION EFFECTS; RADIATIONS; RODENTS; SYMPATHOMIMETICS; VERTEBRATES

Optional Information

Notes
Imprint:Travaux Scientifiques des chercheurs du Service de Sante des Armees durant l'annee 1989.