Published February 2020 | Version v1
Journal article

Research progress of 6-[18F] fluoro-L-dopa PET/CT imaging

  • 1. Department of Nuclear Medicine, Peking Union, Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing Key Laboratory of Molecular Targeted Diagnosis and Therapy in Nuclear Medicine, Beijing (China)

Description

6-[18F] fluoro-L-dopa (18F-DOPA) is a levodopa analogue. 18F-DOPA PET/CT imaging is considered as an ideal tool in the diagnosis and evaluation of Parkinson's disease, brain tumors, pheochromocytoma/paraganglioma, neuroblastoma, gastrointestinal carcinoid, medullary thyroid cancer and congenital hyperinsulinemia. This paper reviews the synthesis, mechanism of localization, imaging procedures, clinical indications and research advances of 18F-DOPA. (authors)

Additional details

Publishing Information

Journal Title
Chinese Journal of Nuclear Medicine and Molecular Imaging
Journal Volume
40
Journal Issue
2
Journal Page Range
p. 113-117
ISSN
2095-2848

Optional Information

Notes
54 refs.; http://dx.doi.org/10.3760/cma.j.issn.2095-2848.2020.02.012