Published January 1974
| Version v1
Journal article
Effect of prostaglandin F/sub 2a/ (PGF/sub 2a/) on venous contractility and 45Ca uptake
Description
SummaryPGF2α enhanced the contractile responses of superfused helical strips of canine cutaneous venous smooth muscle to norepinephrine and the ionic stimulant, barium chloride, in the absence of any significant effect of PGF2α on venous tone. PGF2α also enhanced norepinephrine-induced 45Ca uptake as well as the rate of 45Ca exchange. It was concluded that PGF2α acts to enhance smooth muscle membrane permeability to calcium ion. In addition, it appears that PGF2α may act within the smooth muscle cell to enhance the rate of transcellular calcium exchange.
Additional details
Identifiers
Publishing Information
- Journal Title
- Experimental Biology and Medicine
- Journal Volume
- 145
- Journal Issue
- 1
- Series
- Proc. Soc. Exp. Biol. Med.
- Journal Page Range
- 80-84
- ISSN
- 1535-3702
INIS
- Country of Publication
- United States
- Country of Input or Organization
- United States
- INIS RN
- 5124818
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Descriptors DEI
- BARIUM CHLORIDES; BIOLOGICAL EFFECTS; CALCIUM IONS; CALCIUM 45; MEMBRANES; MUSCLES; NORADRENALINE; PERMEABILITY; PROSTAGLANDIN; RADIONUCLIDE KINETICS; UPTAKE; VEINS
- Descriptors DEC
- ADRENAL HORMONES; ALKALINE EARTH METAL COMPOUNDS; BARIUM COMPOUNDS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BLOOD VESSELS; CALCIUM ISOTOPES; CARDIOVASCULAR SYSTEM; CHARGED PARTICLES; CHLORIDES; CHLORINE COMPOUNDS; DAYS LIVING RADIOISOTOPES; DRUGS; EVEN-ODD NUCLEI; HALIDES; HALOGEN COMPOUNDS; HORMONES; INTERMEDIATE MASS NUCLEI; IONS; ISOTOPES; NUCLEI; RADIOISOTOPES; SYMPATHOMIMETICS
Optional Information
- Notes
- Updated automatically by Metadata and Full-Text Enrichment Agent