Investigation of phytochemical, anti microbial activities of justicia gendarussa and justicia adhatoda

The aim of the study was to explore the Phytochemicals (Alkaloids, Flavonoids, Terpenes, Tannins, Saponinsand Phenols) in root, stem and leaves of Justicia gendarussa and Justicia adhatoda and to correlate it with inhibition of microbes.Alkaloids, flavonoids and phenols were present in both the selected plants while saponins were not detected in the same plants.All fractions of root stem and leaves samples of Justicia gendarussa were active against the selected bacterial strains Enterococcus faecalis, Salmonella typhii, Proteus mirabilis, Staphylococcus aureus, Escherichia coli and Klebsiella pneumoniae except n-hexane fraction of the plant which was fund inactive. Among fractions obtained from root of Justicia gendarussa, the chloroform fraction showed highest zone of inhibition 27 mm against Staphylococcus aureus. While the crude extract and fractionsderived from different parts of Justicia adhatoda showed moderate to good activities against all tested bacteria giving range of inhibition zones from 14 mm to 28 mm. our research plants also showed good antifungal activities against the four tested fungi. (author)