Published April 1989
| Version v1
Journal article
'Scan GFR' as an alternative to 51Cr-EDTA clearance
- 1. Dulwich Hospital, London (UK). Renal Unit
- 2. King's Coll. Hospital, London (UK). Nuclear Medicine Dept.
Description
In this report 39 patients had their GFR assessed by 51Cr-EDTA in a single shot-multiple sampling technique and also by measuring the quantitative renal uptake of 99mTc-DTPA during a standard renal imaging test. The results showed a correlation coefficient of 0.96 between the two techniques. By using linear regression analysis the GFR was derived from the % renal uptake of DTPA in a further series of 24 patients in whom the 51Cr-EDTA method was also employed. The two methods were compared and showed a correlation coefficient of 0.94 with a mean GFR difference of 7 ± 4.5 ml/min over a 51Cr-EDTA range of 38-150 ml/min. (orig.)
Abstract (German)
Bei 39 Patienten wurde der GFR durch mehrfache Blutproben im fallenden Blutspiegel nach Bolusinjektion von 31Cr-EDTA bestimmt im Vergleich zu einem quantitativen renalen 99mTc-DTPA-Uptake im Rahmen der Standard-Szintigraphie. Beide Verfahren korrelierten mit r = 0,96. Bei weiteren 24 Untersuchungen ergab sich wiederum ein r = 0,94 mit mittleren GFR-Abweichungen von 7 ± 4,5 ml/min ueber einen GFR-Bereich von 38-150 ml/min (51Cr-EDTA-Clearance). (orig.)Additional details
Publishing Information
- Journal Title
- Nuc Compact
- Journal Volume
- 20
- Journal Issue
- 2
- Series
- Nuc Compact.
- Journal Page Range
- 44-46
- ISSN
- 0344-3752
- CODEN
- CNNMA
INIS
- Country of Publication
- Germany
- Country of Input or Organization
- Germany
- INIS RN
- 20076487
- Subject category
- S62: RADIOLOGY AND NUCLEAR MEDICINE;
- Descriptors DEI
- CHROMIUM 51; COMPARATIVE EVALUATIONS; DIAGNOSIS; DTPA; EDTA; ISOMERIC NUCLEI; KIDNEYS; PATIENTS; RENAL CLEARANCE; SCINTISCANNING; STATISTICS; TECHNETIUM 99; UPTAKE
- Descriptors DEC
- AMINO ACIDS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BODY; CARBOXYLIC ACIDS; CHELATING AGENTS; CHROMIUM ISOTOPES; CLEARANCE; COUNTING TECHNIQUES; DAYS LIVING RADIOISOTOPES; DIAGNOSTIC TECHNIQUES; DRUGS; ELECTRON CAPTURE RADIOISOTOPES; EVALUATION; EVEN-ODD NUCLEI; EXCRETION; HOURS LIVING RADIOISOTOPES; INTERMEDIATE MASS NUCLEI; INTERNAL CONVERSION RADIOISOTO; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; MATHEMATICS; NUCLEI; ODD-EVEN NUCLEI; ORGANIC ACIDS; ORGANIC COMPOUNDS; ORGANS; RADIOISOTOPE SCANNING; RADIOISOTOPES; RADIOPROTECTIVE SUBSTANCES; RESPONSE MODIFYING FACTORS; TECHNETIUM ISOTOPES; YEARS LIVING RADIOISOTOPES