Published February 25, 2010 | Version v1
Journal article

Angiogenesis and Melanoma

  • 1. Department of Human Anatomy and Histology, University of Bari Medical School, Piazza G. Cesare, 11, Policlinico 70124, Bari (Italy)

Description

Angiogenesis occurs in pathological conditions, such as tumors, where a specific critical point in tumor progression is the transition from the avascular to the vascular phase. Tumor angiogenesis depends mainly on the release by neoplastic cells of growth factors specific for endothelial cells, which are able to stimulate the growth of the host's blood vessels. This article summarizes the literature concerning the relationship between angiogenesis and human melanoma progression. The recent applications of antiangiogenic agents which interfere with melanoma progression are also described

Availability note (English)

Available from http://dx.doi.org/10.3390/cancers2010114; Available from http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827594

Additional details

Publishing Information

Journal Title
Cancers (Basel)
Journal Volume
2
Journal Issue
1
Journal Page Range
p. 114-132
ISSN
2072-6694

INIS

Country of Publication
Switzerland
Country of Input or Organization
International Atomic Energy Agency (IAEA)
INIS RN
47001856
Subject category
S60: APPLIED LIFE SCIENCES; S62: RADIOLOGY AND NUCLEAR MEDICINE;
Descriptors DEI
ANGIOGENESIS; BLOOD VESSELS; GROWTH FACTORS; MELANOMAS
Descriptors DEC
BODY; CARCINOMAS; CARDIOVASCULAR SYSTEM; DISEASES; EPITHELIOMAS; MITOGENS; NEOPLASMS; ORGANIC COMPOUNDS; ORGANS; PROTEINS

Optional Information

Copyright
Copyright (c) 2010 by the authors
Notes
PMCID: PMC3827594; PMID: 24281035; PUBLISHER-ID: cancers-02-00114; OAI: oai:pubmedcentral.nih.gov:3827594; licensee Molecular Diversity Preservation International, Basel, Switzerland.; This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).