Published 1976 | Version v1
Report Metadata-only

In vitro effects of 1,8 MeV neutrons on human peripheral lymphocyte chromosomes

Creators

  • 1. Nauchno-Izsledovatelski Inst. po Radiologiya i Radiatsionna Khigiena, Sofia (Bulgaria)

Description

Human peripheral lymphocyte cultures were exposed in vitro to 1,8 MeV neutrons. Dose-response curves are presented for various types structural chromosome anomalies and compared to relevant X-ray data. For one-break aberrations, a linear dose relationship and an RBE value of 5 were observed, while two-break aberrations (dicentrics and rings) showed a non-linear relationship and an RBE of 2,5 - 3. With neutron doses of intermediate level (50-100 rad), chromosome aberrations revealed no Poisson distribution pattern between cells. (author)

Additional details

Additional titles

Original title (Bulgarian)
Dejstvie in vjtro na neutroni s energiya 1,8 Mev vyrkhu choveshki khromozomi ot periferna kryv

Publishing Information

Imprint Title
Second national conference on medical biology and genetics with international participation and symposium on population genetics and demography of hereditary diseases
Imprint Pagination
p. 38.
Report number
INIS-mf--3315

Conference

Title
2. national conference on medical biology and genetics with international participation and symposium on population genetics and demography of hereditary diseases.
Dates
2 Oct 1976.
Place
Varna, Bulgaria.

INIS

Country of Publication
Bulgaria
Country of Input or Organization
Bulgaria
INIS RN
8324556
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
Resource subtype / Literary indicator
Conference
Descriptors DEI
CELL CULTURES; CHROMOSOMAL ABERRATIONS; DOSE-RESPONSE RELATIONSHIPS; LYMPHOCYTES; NEUTRONS; RBE
Descriptors DEC
ANIMAL CELLS; BARYONS; BIOLOGICAL MATERIALS; BLOOD; BLOOD CELLS; BODY FLUIDS; CONNECTIVE TISSUE CELLS; ELEMENTARY PARTICLES; FERMIONS; HADRONS; LEUKOCYTES; MUTATIONS; NUCLEONS; SOMATIC CELLS

Optional Information

Notes
Published in summary form only. English abstract available. Imprint:Vtora natsionalna konferentsiya po meditsinska biologiya i genetika s mezhdunarodno uchastie i simpozium po populatsionna genetika i demografiya na nasledstvenite bolesti.;Rezyumeta.