Published August 1989 | Version v1
Journal article

Total synthesis of [7-14C]-(+-)-colchicine

  • 1. Paris-5 Univ., 75 (France). Lab. de Chimie et Biochimie Pharmacologiques et Toxicologiques

Description

The synthesis of (±)-colchicine labelled with carbon-14 at the 7-position of the B ring was achieved by a sixteen step sequence with an overall radiochemical yield of 2.5% from [Ba14CO3] (Specific activity: 55 mCi-mmol-1). (author)

Additional details

Publishing Information

Journal Title
Journal of Labelled Compounds and Radiopharmaceuticals
Journal Volume
27
Journal Issue
8
Series
J. Labelled Compd. Radiopharm.
Journal Page Range
927-937
ISSN
0362-4803
CODEN
JLCRD

Conference

Title
3. international symposium on the synthesis and applications of isotopically labelled compounds.
Dates
17-21 Jul 1988.
Place
Innsbruck (Austria).

INIS

Country of Publication
United Kingdom
Country of Input or Organization
United Kingdom
INIS RN
21030684
Subject category
S38: RADIATION CHEMISTRY, RADIOCHEMISTRY AND NUCLEAR CHEMISTRY;
Resource subtype / Literary indicator
Conference
Descriptors DEI
CARBON 14 COMPOUNDS; CHEMICAL PREPARATION; COLCHICINE; LABELLING
Descriptors DEC
ALKALOIDS; ANTIMITOTIC DRUGS; ANTIPYRETICS; CARBON COMPOUNDS; CENTRAL NERVOUS SYSTEM AGENTS; CENTRAL NERVOUS SYSTEM DEPRESS; DRUGS; ORGANIC COMPOUNDS; SYNTHESIS