Published 1991 | Version v1
Book

Photoenzymes: A novel class of biological catalysis

  • 1. Cornell Univ., Ithaca, NY (United States)

Description

DNA photolyase catalyzes the photochemical monomerization of pyrimidine photodimers in UV-damaged DNA. Based on model studies, mechanisms involving fragmentation of the photodimer cation radical or anion radical have been proposed for the enzymatic reaction. A combination of isotope effect studies and radical trapping experiments, designed to differentiate between these mechanisms is described. Protochlorophyllide reductase, the only other characterized example of a light-dependent enzyme, catalyzes the photochemical reduction of protochlorophyllide. The regiochemistry and stereochemistry of this reaction is described

Additional details

Publishing Information

Publisher
American Chemical Society.
Imprint Place
Washington, DC (United States)
Imprint Title
American Chemical Society. Division of Organic Chemistry
Imprint Pagination
117 p.
Journal Page Range
p. 67, Paper ORGN 216.

Conference

Title
201. American Chemical Society (ACS) national meeting.
Dates
14-19 Apr 1991.
Place
Atlanta, GA (United States).

Optional Information

Secondary number(s)
CONF-910402--.