Published 1982
| Version v1
Journal article
Permeability of the blood-brain barrier in the rat after local proton irradiation
Creators
- 1. Uppsala Univ. (Sweden). Gustaf Werner Inst.
- 2. Institute of Theoretical and Experimental Physics, Moscow, USSR
Description
Rats were irradiated laterally through the brain with 200 MeV protons. The beam was of circular cross-section with a diameter of 5 or 7 mm. The doses were 50, 70, 100 and 150 Gy. After irradiation the rats were examined several times by use of injected 99Tcsup(m) pertechnetate. The uptake of the substance increased to a maximum after 20 to 30 days and then decreased to a normal level. Differences in maximum uptake with respect to dose were significant only for the smaller beam diameter. (Auth.)
Additional details
Publishing Information
- Journal Title
- Acta Radiol., Oncol., Radiat. Ther., Phys. Biol.
- Journal Volume
- 21
- Journal Issue
- 4
- Series
- Acta Radiol., Oncol., Radiat. Ther., Phys. Biol.
- Journal Page Range
- 267-271
INIS
- Country of Publication
- Sweden
- Country of Input or Organization
- Sweden
- INIS RN
- 14749741
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Resource subtype / Literary indicator
- Numerical Data
- Descriptors DEI
- BLOOD-BRAIN BARRIER; EXPERIMENTAL DATA; LABELLED COMPOUNDS; LOCAL IRRADIATION; LOCAL RADIATION EFFECTS; MEV RANGE 100-1000; PERMEABILITY; PERTECHNETATES; PROTONS; RADIATION DOSES; RATS; TECHNETIUM 99; UPTAKE
- Descriptors DEC
- ANIMALS; BARYONS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BIOLOGICAL EFFECTS; BIOLOGICAL RADIATION EFFECTS; CATIONS; CHARGED PARTICLES; DATA; ELEMENTARY PARTICLES; ENERGY RANGE; FERMIONS; HADRONS; HOURS LIVING RADIOISOTOPES; HYDROGEN IONS; HYDROGEN IONS 1 PLUS; INFORMATION; INTERMEDIATE MASS NUCLEI; IONS; IRRADIATION; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; MAMMALS; MEV RANGE; NUCLEI; NUCLEONS; NUMERICAL DATA; ODD-EVEN NUCLEI; OXYGEN COMPOUNDS; RADIATION EFFECTS; RADIOISOTOPES; RODENTS; TECHNETIUM COMPOUNDS; TECHNETIUM ISOTOPES; TRANSITION ELEMENT COMPOUNDS; VERTEBRATES; YEARS LIVING RADIOISOTOPES