Published 1978
| Version v1
Journal article
Ageing and sensitivity of mouse premeiotic male germ cells
Description
Male BALB/c mice were whole body exposed to 0, 100, 200 or 300 R of X-rays or were given an i.p. injection of 5 mg/kg of thio-TEPA at 3 months or at 12 months of age. One hundred days after treatment the testes were examined for the presence of reciprocal translocations induced in spermatogonia and detectable in the dividing spermatocytes. Our results show that ages does not influence the yield of scorable chromosome rearrangements
Abstract (French)
Des souris males agees de 3 ou de 12 mois ont ete irradiees sur tout le corps avec une dose de 0, 100, 200 ou 300 R de rayons X ou ont recu une injection intraperitoneale de 5 mg de thio-TEPA par kg de poids. Cent jours apres le traitement, nous avons examine les spermatocytes en division pour y denombrer les translocations reciproques produites dans les spermatogonies, et qui sont compatibles avec la survie et la multiplication cellulaire. Nos resultats demontrent qu'il n'y a aucune difference dans les taux d'anomalies entre les animaux traites a 3 ou a 12 moisAdditional details
Additional titles
- Original title (French)
- Influence de l'age sur la sensibilite des spermatogonies de la souris a l'action des mutagenes
Publishing Information
- Journal Title
- C. R. Seances Soc. Biol. Fil.
- Journal Volume
- 172
- Journal Issue
- 5
- Series
- C. R. Seances Soc. Biol. Fil.
- Journal Page Range
- 1029-1032
INIS
- Country of Publication
- France
- Country of Input or Organization
- France
- INIS RN
- 11521765
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Descriptors DEI
- AGE DEPENDENCE; CHROMOSOMAL ABERRATIONS; MICE; MUTAGENS; RADIOSENSITIVITY; SPERMATOGONIA; WHOLE-BODY IRRADIATION; X RADIATION
- Descriptors DEC
- ANIMALS; ELECTROMAGNETIC RADIATION; EXTERNAL IRRADIATION; GERM CELLS; IONIZING RADIATIONS; IRRADIATION; MAMMALS; MUTATIONS; RADIATIONS; RODENTS; VERTEBRATES