Treatment results of malignant lymphoma of the brain

Retrospective analysis of patients with malignant lymphoma of the brain was carried out. All cases were mainly treated with radiation therapy. Overall survival was 44 % and 37 % at two and five year. Survival was statistically better for patients with diffuse medium-sized cell or diffuse mixed type compared with diffuse large cell type by the LSG classification, for the age group < 50 years compared with ≥ 50 years, and for the group with Karnofsky Index ≥ 50 % compared with ≤ 40 %. In 11 of 15 patients the first recurrent site was the central nervous system. (author)