Published September 1999 | Version v1
Journal article Metadata-only

The immunological phenotype and ultrastructure of blood lymphocytes of children with the diagnosis of thyroid cancer who lived near the Chernobyl NPS

Creators

  • 1. Kievskij Nauchno-Issledovatel'skij Inst. Ehndokrinologii i Obmena Veshchestv, Kiev (Ukraine)

Description

On the flow cytometric and electron microscopic study of blood cells in children with papillary thyroid cancer, who lived near the Chernobyl Nuclear Power Station, we revealed a decrease in the number and changes in the ultrastructure of T-lymphocytes (CD3+ cells), T-helpers (CD4+ cells), and NK cells (CD56+cells) as well as eosinophilia. We suggest that the impairment of T-cellular and natural immunity may be a promoting factor of the malignant transformation of thyrocytes induced by radioiodine

Additional details

Additional titles

Original title (Russian)
Иммунологический фенотип и ультраструктура лимфоцитов крови детей, проживавших вблизи Чернобильской AEhS, у которых диагностирован рак щитовидной железы

Publishing Information

Journal Title
Dopovyidyi Natsyional'noyi Akademyiyi Nauk Ukrayini
Journal Issue
no.9
Journal Page Range
p. 186-190
ISSN
1025-6415

INIS

Country of Publication
Ukraine
Country of Input or Organization
Ukraine
INIS RN
31017241
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS; S21: SPECIFIC NUCLEAR REACTORS AND ASSOCIATED PLANTS;
Descriptors DEI
BLOOD CELLS; CARCINOMAS; CHERNOBYLSK-4 REACTOR; CHILDREN; DELAYED RADIATION EFFECTS; IMMUNITY; LYMPHOCYTES; PHENOTYPE; REACTOR ACCIDENTS; THYROID
Descriptors DEC
ACCIDENTS; AGE GROUPS; ANIMAL CELLS; BIOLOGICAL EFFECTS; BIOLOGICAL MATERIALS; BIOLOGICAL RADIATION EFFECTS; BLOOD; BLOOD CELLS; BODY; BODY FLUIDS; CONNECTIVE TISSUE CELLS; DISEASES; ENDOCRINE GLANDS; ENRICHED URANIUM REACTORS; GLANDS; GRAPHITE MODERATED REACTORS; LEUKOCYTES; LWGR TYPE REACTORS; MATERIALS; NEOPLASMS; ORGANS; POWER REACTORS; RADIATION EFFECTS; REACTORS; SOMATIC CELLS; THERMAL REACTORS; WATER COOLED REACTORS