Synthesis of novel PETT analogues: 3,4-dimethoxy phenyl ethyl 1,3,5-triazinyl thiourea derivatives and their antibacterial and anti-HIV studies

3,4-Dimethoxy phenyl ethyl-1,3,5-triazinyl thiourea derivatives (8a-o and 9a-o) were prepared by condensation of 2,4,6-trichloro-1,3,5-s-triazine (1) with 4-hydroxy coumarin (2), 3,4-dimethoxy phenyl ethyl thiourea (4) and various substituted phenyl urea/thiourea (6a-o/7a-o) and tested for their antibacterial and anti-HIV activities against different microorganisms. The structures of novel synthesized compounds have been established on the basis of 1H NMR, IR and Elemental Analysis. (author)