The evaluation of dobutamine 99mTc-MIBI myocardial perfusion imaging in the diagnosis of coronary heart disease
Description
The method and the clinical value of dobutamine stress test as a substitute for exercise test in 99mTc-MIBI myocardial perfusion imaging was investigated. 40 Patients were intravenously infused with dobutamine through IVAC syringe pumps by incremental doses, and 99mTc-MIBI was injected at the peak dobutamine heart rate. The myocardial imaging was then performed. The rest myocardial imaging was done after 48 hours. 30 of the 31 patients with coronary heart disease showed reversible perfusion defects in dobutamine 99mTc-MIBI myocardial perfusion images and 7 of the 9 patients without coronary heart disease showed normal images. The sensitivity of this test was 96.8% and the specificity 77.8%. None of the studies was discontinued due to dobutamine side effect. Dobutamine 99mTc-MIBI myocardial perfusion imaging is a safe and sensitive method in the diagnosis of coronary heart disease
Additional details
Publishing Information
- Journal Title
- Chinese Journal of Nuclear Medicine
- Journal Volume
- 16
- Journal Issue
- 1
- Journal Page Range
- p. 20-22.
- ISSN
- 0253-9780
- CODEN
- CITCDE
INIS
- Country of Publication
- China
- Country of Input or Organization
- China
- INIS RN
- 27068232
- Subject category
- S62: RADIOLOGY AND NUCLEAR MEDICINE;
- Descriptors DEI
- CARDIOVASCULAR AGENTS; CARDIOVASCULAR DISEASES; DIAGNOSIS; LABELLED COMPOUNDS; MYOCARDIUM; PERFUSED ORGANS; SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY; TECHNETIUM 99
- Descriptors DEC
- BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BODY; CARDIOVASCULAR SYSTEM; COMPUTERIZED TOMOGRAPHY; DISEASES; DRUGS; EMISSION COMPUTED TOMOGRAPHY; HEART; HOURS LIVING RADIOISOTOPES; INTERMEDIATE MASS NUCLEI; INTERNAL CONVERSION RADIOISOTOPES; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; MUSCLES; NUCLEI; ODD-EVEN NUCLEI; ORGANS; RADIOISOTOPES; TECHNETIUM ISOTOPES; TOMOGRAPHY; YEARS LIVING RADIOISOTOPES