Epilepsy surgery in children. What the radiologist needs to know
Creators
- 1. Department of Radiology, Great Ormond Street Hospital NHS Foundation Trust, London (United Kingdom)
- 2. Department of Neurology, Great Ormond Street Hospital NHS Foundation Trust, London (United Kingdom)
- 3. Department of Neurosurgery, Great Ormond Street Hospital NHS Foundation Trust, London (United Kingdom)
Description
This review updates the radiologist on current epilepsy surgery practice in children, with a specific focus on the role of imaging in pre-surgical work-up, current and novel surgical techniques, expected post-surgical imaging appearances and important post-operative complications. A comprehensive review of the current and emerging international practices in paediatric epilepsy surgical planning and post-operative imaging is provided with details on case-based radiological findings. A detailed discussion of the pathophysiology and imaging features of different epileptogenic lesions will not be discussed as this is not the objective of this paper. Epilepsy surgery can be an effective method to control seizures in certain children with drug-resistant focal epilepsy. Early surgery in selected appropriate cases can lead to improved cognitive and developmental outcome. Advances in neurosurgical techniques, imaging and neuroanaesthesia have driven a parallel expansion in the array of epilepsy conditions which are potentially treatable with surgery. The range of surgical options is now wide, including minimally invasive ablative procedures for small lesions such as hypothalamic hamartomata, resections for focal lesions like hippocampal sclerosis and complex disconnective surgeries for multilobar conditions like Sturge Weber Syndrome and diffuse cortical malformations. An awareness of the surgical thinking when planning epilepsy surgery in children, and the practical knowledge of the operative steps involved will promote more accurate radiology reporting of the post-operative scan.
Availability note (English)
Available from: http://dx.doi.org/10.1007/s00234-020-02448-2Additional details
Identifiers
Publishing Information
- Journal Title
- Neuroradiology
- Journal Volume
- 62
- Journal Issue
- 9
- Journal Page Range
- p. 1061-1078
- ISSN
- 0028-3940
- CODEN
- NRDYAB
INIS
- Country of Publication
- Germany
- Country of Input or Organization
- Germany
- INIS RN
- 51107820
- Subject category
- S62: RADIOLOGY AND NUCLEAR MEDICINE;
- Descriptors DEI
- ABLATION; BRAIN; CHILDREN; CONGENITAL MALFORMATIONS; DIFFUSION; ELECTROENCEPHALOGRAPHY; EPILEPSY; HEMOGLOBIN; IMAGE PROCESSING; IMPLANTS; NMR IMAGING; PEDIATRICS; PLANNING; POSITRON COMPUTED TOMOGRAPHY; RELAXATION TIME; SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY; SURGERY; WEIGHTING FUNCTIONS
- Descriptors DEC
- AGE GROUPS; ANIMALS; BODY; CARBOXYLIC ACIDS; CENTRAL NERVOUS SYSTEM; COMPUTERIZED TOMOGRAPHY; DIAGNOSTIC TECHNIQUES; DISEASES; EMISSION COMPUTED TOMOGRAPHY; FUNCTIONS; GLOBINS; HETEROCYCLIC ACIDS; HETEROCYCLIC COMPOUNDS; MALFORMATIONS; MAMMALS; MAN; MEDICINE; NERVOUS SYSTEM; NERVOUS SYSTEM DISEASES; ORGANIC ACIDS; ORGANIC COMPOUNDS; ORGANIC NITROGEN COMPOUNDS; ORGANS; PATHOLOGICAL CHANGES; PIGMENTS; PORPHYRINS; PRIMATES; PROCESSING; PROTEINS; TOMOGRAPHY; VERTEBRATES