Published June 2014 | Version v1
Journal article

Performance comparison of poly zirconium compound (PZC) kaken with polymer based zirconium (PBZ) from PTRR for 99Mo/99mTC generator column

  • 1. Pusat Teknologi Radioisotop dan Radiofarmaka - BATAN, Kawasan Puspiptek, Serpong, Tangerang Selatan 15314 (Indonesia)

Description

99Mo/99mTc generator produce radioisotopes 99mTc which is a major medical on the world radioisotopes are used for diagnosis in the field of nuclear medicine. Five (5) of a nuclear reactor in the world producing radioisotopes 99Mo main (parent of 99mTc radioisotope) from uranium fission seriously impaired, as well as the production of medical radioisotopes 99mTc. Because the parent radioisotope 99Mo production process using neutron activation method from molybdenum targets do. Radioisotope 99Mo from neutron activation results this has kind of low radioactivity, so it is not appropriate to use the alumina column, because the absorption capacity of molybdenum small (Mo ± 2 mg/g Al). As an alternative use of zirconium polymer compound having a high absorption capacity (270 mg/g). This study discusses the performance comparison Poly Zirconium Compound (PZC) by Kaken Co. Japan and Polymer Based Zirconium (PBZ) synthesized by PTRR, BATAN. This study establishes absorption capacity, absorption efficiency, impurity 99Mo , separation efficiency of 99mTc and of the elution profile. Results study, PZC performance parameters for the aforementioned 210.62 mg/g, 77.4%, 0.0187 µCi/mCi and 0.0132 µCi/mCi, 276.35 mCi (86.15%), respectively. As for PBZ, 188.81 mg/g, 79.33%, 0.2337 µCi/mCi and 31.5615 µCi/mCi, 43.39 mCi (67.90%). 99mTc elution profile of the PZC and PBZ almost similar, that 99mTc radioactivity levels obtained before the eluent volume reached 10 mL. (author)

Additional details

Additional titles

Original title (Indonesian)
Perbandingan unjuk kerja poly zirconium compound (PZC) dari kaken dengan polimer berbasis zirkonium (PBZ) dari PTRR untuk kolom generator 99Mo/99mTc

Publishing Information

Journal Title
Urania
Journal Volume
20
Journal Issue
2
Journal Page Range
p. 100-108
ISSN
0852-4777

Optional Information

Notes
7 refs.; 4 tabs.; 2 figs.