Published February 2003 | Version v1
Journal article Metadata-only

Mathematical model of interstitial intervention with beta source for tumor therapy

Creators

  • 1. Beijing Union Medical College, Beijing (China). Cancer Hospital, Dept. of Nuclear Medicine
  • 2. General hospital of PLA, Beijing (China). Dept. of Nuclear Medicine

Description

For the entire process of intervention tumor therapy through interstitial injection of β-radionuclides, mathematical models were discussed in terms of absorbed dose distribution, dose effect relationship and tumor curability levels. The following mathematical formulae for the tumor therapy were recommended, which were based, respectively, on, 1) radiation dose rate distribution in tumor volume, 2) clonogenic cells survival fraction distribution in tumor and 3) tumor control probability. The mathematical formulae could be used as the basic theory in the tumor treatment planning for interstitial intervention with β-radionuclides

Additional details

Publishing Information

Journal Title
Nuclear Techniques
Journal Volume
26
Journal Issue
2
Journal Page Range
p. 159-162
ISSN
0253-3219

INIS

Country of Publication
China
Country of Input or Organization
China
INIS RN
35063172
Subject category
S62: RADIOLOGY AND NUCLEAR MEDICINE;
Descriptors DEI
BETA DECAY RADIOISOTOPES; MATHEMATICAL MODELS; NEOPLASMS; PROBABILISTIC ESTIMATION; RADIATION DOSE DISTRIBUTIONS; RADIATION DOSES; RADIATION SOURCE IMPLANTS; RADIOTHERAPY; SURVIVAL CURVES
Descriptors DEC
CALCULATION METHODS; DISEASES; DOSES; IMPLANTS; ISOTOPES; MEDICINE; NUCLEAR MEDICINE; RADIATION SOURCES; RADIOISOTOPES; RADIOLOGY; THERAPY