Clinical study of ¹³¹I treatment in lung metastases of differentiated thyroid carcinoma

Objective: To investigate the clinical efficiency and side effect of ¹³¹I treatment of differentiated thyroid cancer (DTC) with lung metastases. Methods: Retrospective statistical analysis of 32 DTC patients with lung metastases after surgery received ¹³¹I treatment in our hospital in the past decade. Before and after ¹³¹I treatment, to observed the changes of whole body scan with ¹³¹I, cervical and thoracic CT and serum thyroglobulin. Meantime, to analyzed the changes of peripheral blood, liver and kidney function. Results: The total effective rate of ¹³¹I treatment DTC with lung metastases reached to 84.4%. Also, different kind of blood cell, hemoglobin in peripheral blood, liver and kidney function were not affected by this method. Conclusion: Application of ¹³¹I treatment of DTC with lung metastases was a good means with significant clinical effect and few adverse reactions. (authors)