Published October 5, 1995 | Version v1
Patent Metadata-only

New iodized boron compounds useful as X-ray contrasting agents, and pharmaceutical compositions containing them

Creators

Description

The invention relates to new organic boron compounds having a monomer structure (I): [BxCyH(x+ytw)ItTw], 2/rQ and a dimer structure (II): ([B12H(12-tw)ItZw]-[B12H(12-w)ItZw), 4/rQ, characterized in that they contain high molar percentage of iodine, and are useful as radio-opaque agents in uroangiography, cardiography, etc., as well as for selectively visualizing organs or body systems such as the liver, the spleen or the lymphatic system. The compound having the general formulas (I) and (II) are also useful in the selective therapy of tumors. The invention also relates to pharmaceutical preparations which contain the claimed compound having the general formulas (I) and (II). (author)

Availability note (English)

Available from WIPO, 34, chemin des Colombettes, CH-1211 Geneva (CH).

Additional details

Publishing Information

Imprint Pagination
30 p.
IPC:
Int. Cl. C07F 5/02; A61K 49/04.
IPC
Int. Cl. C07F 5/02; A61K 49/04.
Patent number
WO patent document 9526353/A1/

INIS

Country of Publication
Switzerland
Country of Input or Organization
Switzerland
INIS RN
27010015
Subject category
S37: INORGANIC, ORGANIC, PHYSICAL AND ANALYTICAL CHEMISTRY; S62: RADIOLOGY AND NUCLEAR MEDICINE;
Resource subtype / Literary indicator
Non-conventional Literature
Descriptors DEI
CONTRAST MEDIA; DRUGS; IODINE; LIVER; LYMPHATIC SYSTEM; NEOPLASMS; ORGANIC BORON COMPOUNDS; SPLEEN; THERAPY; X RADIATION
Descriptors DEC
BODY; DIGESTIVE SYSTEM; DISEASES; ELECTROMAGNETIC RADIATION; ELEMENTS; GLANDS; HALOGENS; IONIZING RADIATIONS; MEDICINE; NONMETALS; ORGANIC COMPOUNDS; ORGANS; RADIATIONS

Optional Information

Secondary number(s)
ES patent application 9400034.