Clinical significance of determination of changes of serum IL-6, hs-CRP and saliva secretory IgA levels after treatment in patients with periodontitis
Description
Objective: To explore the clinical significance of changes of serum IL-6, hs-CRP and saliva secretory IgA levels after treatment in patients with periodontitis. Methods: Serum IL-6, saliva secretory IgA (with RIA) and serum hs-CRP (with immuno-tarbility method) levels were measured in 42 patients with periodontitis both before and after treatment as well as in 35 controls. Results: Before treatment serum IL-6, hs-CRP and saliva secretory IgA levels in the patients wree significantly higher than those in controls (P<0.01). After treatment for one month the serum IL-6, hs-CRP levels in the patients were not much different from those in controls (P>0.05). However, the saliva secreatory IgA levels were still significantly higher than those in controls (P<0.05). Conclusion: There was disturbance of immunomodulation in patients with periodontitis as expressed by the changes of cytokines levels in the course of the diseases. (authors)
Additional details
Publishing Information
- Journal Title
- Journal of Radioimmunology
- Journal Volume
- 22
- Journal Issue
- 3
- Journal Page Range
- p. 211-213
- ISSN
- 1008-9810
INIS
- Country of Publication
- China
- Country of Input or Organization
- China
- INIS RN
- 43001562
- Subject category
- S62: RADIOLOGY AND NUCLEAR MEDICINE;
- Descriptors DEI
- BLOOD SERUM; DENTISTRY; DIAGNOSIS; DISEASES; GLOBULINS-ALPHA; IMMUNOGLOBULINS; LYMPHOKINES; MEDICAL SURVEILLANCE; PATHOGENESIS; PATIENTS; RADIOIMMUNOASSAY; SALIVA; THERAPY
- Descriptors DEC
- BIOASSAY; BIOLOGICAL MATERIALS; BLOOD; BLOOD PLASMA; BODY FLUIDS; DIAGNOSTIC TECHNIQUES; GLOBULINS; GROWTH FACTORS; IMMUNOASSAY; ISOTOPE APPLICATIONS; MATERIALS; MEDICINE; MITOGENS; ORGANIC COMPOUNDS; PROTEINS; RADIOASSAY; RADIOIMMUNODETECTION; TRACER TECHNIQUES
Optional Information
- Notes
- 1 tab., 6 refs.