Clinical significance of determination of cytokines levels in patients with coronary heart disease
- 1. Department of Cardiology, East hospital of No.1 People's Hospital of Lianyungang, Lianyungang (China)
Description
Objective: To explore the significance of changes of serum IL-6, IL-10, IL-15 and TNF-α levels in patients with coronary heart disease (CHD). Methods: Serum levels of IL-6 TNF-α (with RIA) IL-10, IL-18, levels (with ELA) were measured in 71 patients with CHD (35 SAP, 21 UAP, 15 AMI) and 35 controls. Results: Serum levels of IL-6, IL-10, IL-18 and TNF-α in patients with coronary heart disease were significantly higher than those in the controls (P<0.01 ), Among the CHD patients, the levels of IL-6, IL-10, IL-18 and TNF-α in AMI and UAP groups were significantly higher than those in SAP Group (P< 0.05). Conclusion: Levels of serum pro-inflammatory cytokines IL-6, IL-10, IL-18 and TNF-α levels increased significantly in patients with coronary heart disease especially in those advanced cases. (authors)
Additional details
Publishing Information
- Journal Title
- Journal of Radioimmunology
- Journal Volume
- 19
- Journal Issue
- 4
- Journal Page Range
- p. 293-295
- ISSN
- 1008-9810
INIS
- Country of Publication
- China
- Country of Input or Organization
- China
- INIS RN
- 39096081
- Subject category
- S62: RADIOLOGY AND NUCLEAR MEDICINE;
- Descriptors DEI
- BLOOD SERUM; CARDIOVASCULAR DISEASES; CORONARIES; DIAGNOSIS; ENZYME IMMUNOASSAY; INFLAMMATION; LYMPHOKINES; MYOCARDIAL INFARCTION; PATIENTS; RADIOIMMUNOASSAY; RESPONSE MODIFYING FACTORS
- Descriptors DEC
- ARTERIES; BIOASSAY; BIOLOGICAL MATERIALS; BLOOD; BLOOD PLASMA; BLOOD VESSELS; BODY; BODY FLUIDS; CARDIOVASCULAR DISEASES; CARDIOVASCULAR SYSTEM; DIAGNOSTIC TECHNIQUES; DISEASES; GROWTH FACTORS; IMMUNOASSAY; ISOTOPE APPLICATIONS; MATERIALS; MITOGENS; ORGANIC COMPOUNDS; ORGANS; PATHOLOGICAL CHANGES; PROTEINS; RADIOASSAY; RADIOIMMUNODETECTION; SYMPTOMS; TRACER TECHNIQUES
Optional Information
- Notes
- 1 tab., 9 refs.