Effects of extract of achynanthis bidentatae on CFU-S and hemopoiesis of BFU-E, CFU-E in irradiated mice

Objective: To study the Extract of Achynanthis Bidentatae (ABE) on colony forming unit-spleen (CFU-S) and hemopoiesis of burst forming unit-erythroid (BFU-E), colony forming unit-erythroid (CFU-E) in Irradiated mice. Methods: Using techniques of CFU-S and cell culture of hemopoietic progenitors in vitro, the authors observed the effects of ABE on weight of spleen, CFU-S, BFU-E and CFU-E. Results: It is shown the weight of spleen and the number of CFU-S was increased, but there was no stimulation activity on BFU-E and CFU-E. Conclusion: ABE may stimulate the proliferation of CFU-S, but there was no effect on differentiation of BFU-E and CFU-E. (authors)