Published 2022 | Version v1
Journal article Metadata-only

Added value of nuclear medicine methods in staging. Restaging and follow-up of Merkel-cell carcinoma - review and own clinical experience

Creators

  • 1. Clinic of Nuclear Medicine, University Hospital on Oncology, Sofia (Bulgaria)
  • 2. Clinic of Oncodermatology, University Hospital on Oncology, Sofia (Bulgaria)

Description

Merkel-cell carcinoma (MCC) is a rare cutaneous malignancy with a complex etiology, histopathology and aggressive behavior with high mortality. The necessity for correct staging to define adequate on-time treatment in oncology is undoubtedly influenced by contemporary imaging diagnostics. For MCC however, an established diagnostic algorithm is still missing. Modern hybrid SPECT/ CT and PET/CT nuclear medicine (NM) methods play an essential role for accurate definition of loco-regional lymph node status and whole-body TNM staging and restaging to individualize the therapeutic algorithm. Key words: Merkel-Cell Carcinoma. SPECT/CT. PET/CT. (author)

Abstract (Bulgarian)

Меркел-клетъчният карцином (MKK) е рядък кожен тумор с комплексна етиология, хистопатология и агресивен характер с висока смъртност. Необходимостта от коректно стадиране за определяне на адекватно навременно лечение в онкологията е неизменно свързана със съвременните образно-диагностични подходи. За МКК обаче все още липсва утвърден диагностичен протокол. Модерните хибридни SPECT/CT и РЕТ/СТ нуклеарно-медицински методи имат съществена роля за точно определяне на регионалния лимфонодален статус и целотелесното TNM-стадиране и рестадиране за насочване на индивидуализирания терапевтичен алгоритъм

Additional details

Publishing Information

Journal Title
Rentgenologiya i Radiologiya
Journal Volume
61
Journal Issue
1
Journal Page Range
p. 29-36
ISSN
0486-400X

INIS

Country of Publication
Bulgaria
Country of Input or Organization
Bulgaria
INIS RN
54010289
Subject category
S62: RADIOLOGY AND NUCLEAR MEDICINE;
Descriptors DEI
CARCINOMAS; ETIOLOGY; LYMPH NODES; NUCLEAR MEDICINE; POSITRON COMPUTED TOMOGRAPHY; SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY; SKIN; SKIN DISEASES
Descriptors DEC
BODY; COMPUTERIZED TOMOGRAPHY; DIAGNOSTIC TECHNIQUES; DISEASES; EMISSION COMPUTED TOMOGRAPHY; LYMPHATIC SYSTEM; MEDICINE; NEOPLASMS; ORGANS; TOMOGRAPHY

Optional Information

Notes
6 figs., 29 refs.