Published May 1999
| Version v1
Journal article
Study on the effect and mechanism of tumor inhibition of α-Ti3
Creators
- 1. Food Hygiene Department, Institute of Preventive Medicine (China)
Description
Objective: Tumor inhibition of α-Ti3 on H22 cell, Lewis cell and S180 cell and the effect of α-Ti3 on immune function in tumor mice were observed. Methods: Taking H22 tumor mice as an animal model, the authors measured tumor weight and relative immunologic indexes. Results: The results showed that LD50 of α-Ti3 was 1849.36 mg/kg; α-Ti3 could inhibit tumor and enhance spontaneous proliferation of thymocytes and synergically ConA-induced mitogenic response of splenocytes, and increase DNA synthesis of S period of splenocytes. Conclusion: That α-Ti3 can improve immune function of tumor mice could be one of the mechanisms of tumor inhibition
Additional details
Publishing Information
- Journal Title
- Journal of Norman Bethune University of Medical Sciences
- Journal Volume
- 25
- Journal Issue
- 3
- Journal Page Range
- p. 241-243
- ISSN
- 0253-3707
- CODEN
- PEIPDB
INIS
- Country of Publication
- China
- Country of Input or Organization
- China
- INIS RN
- 31041243
- Subject category
- S62: RADIOLOGY AND NUCLEAR MEDICINE; S38: RADIATION CHEMISTRY, RADIOCHEMISTRY AND NUCLEAR CHEMISTRY;
- Descriptors DEI
- ABDOMEN; CELL PROLIFERATION; DNA; HEPATOMAS; IMMUNITY; INHIBITION; LIVER CELLS; LUNGS; LYMPHOCYTES; MICE; SILICATES; SPLEEN CELLS; THYMOCYTES; TITANIUM SILICATES; TRITIUM; TUMOR CELLS; TUNGSTATES
- Descriptors DEC
- ANIMAL CELLS; ANIMALS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BIOLOGICAL MATERIALS; BLOOD; BLOOD CELLS; BODY; BODY FLUIDS; CARCINOMAS; CONNECTIVE TISSUE CELLS; DISEASES; HYDROGEN ISOTOPES; ISOTOPES; LEUKOCYTES; LIGHT NUCLEI; MAMMALS; MATERIALS; NEOPLASMS; NUCLEI; NUCLEIC ACIDS; ODD-EVEN NUCLEI; ORGANIC COMPOUNDS; ORGANS; OXYGEN COMPOUNDS; RADIOISOTOPES; REFRACTORY METAL COMPOUNDS; RESPIRATORY SYSTEM; RODENTS; SILICATES; SILICON COMPOUNDS; SOMATIC CELLS; TITANIUM COMPOUNDS; TRANSITION ELEMENT COMPOUNDS; TUNGSTEN COMPOUNDS; VERTEBRATES; YEARS LIVING RADIOISOTOPES