Published December 1987
| Version v1
Journal article
Effect of low doses of whole body irradiation on spontaneous lung metastasis of NFSA2ALM1 mouse tumors
Description
The effect of low-dose (10 - 50 cGy) irradiation, delivered as single or fractionated doses, on metastatic development was investigated using NFSA2ALM1 fibrosarcoma and the C3H/HeNrs mouse. Spontaneous lung metastases from tumors transplanted into the leg were suppressed in those mice irradiated with low doses of radiation 12 days after tumor cell inoculation. Abbreviations used: LCFE = lung colony forming efficiency through i.v. injection of tumor cells; SLME = spontaneous lung metastasis efficiency from leg tumors; TD50 = cell number which produces tumors in 50 % of inoculated sites; WBI = Whole body irradiation. (author)
Additional details
Publishing Information
- Journal Title
- Radiat. Med.
- Journal Volume
- 5
- Journal Issue
- 6
- Series
- Radiat. Med.
- Journal Page Range
- 212-214
- ISSN
- 0288-2043
- CODEN
- RAMEE
INIS
- Country of Publication
- Japan
- Country of Input or Organization
- Japan
- INIS RN
- 19092295
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Descriptors DEI
- EXPERIMENTAL NEOPLASMS; LOW DOSE IRRADIATION; LUNGS; METASTASES; MICE; SARCOMAS; WHOLE-BODY IRRADIATION
- Descriptors DEC
- ANIMALS; BODY; DISEASES; EXTERNAL IRRADIATION; IRRADIATION; MAMMALS; NEOPLASMS; ORGANS; RESPIRATORY SYSTEM; RODENTS; VERTEBRATES