Medical use of fast neutrons in radiotherapy and radiography

Over 400 patients have been treated with fast neutrons from a cyclotron at Hammersmith Hospital, London, using 16 MeV deuterons on beryllium. A large variety of malignant disease is included in this trial. A randomized trial of fast neutron therapy for cancer of the mouth and throat is in progress and preliminary results will be given. Fast neutron radiographs are often taken to check the positions of the fields used on the patients. These show no contrast from bone, but demonstrate only the presence of gas-filled cavities. As a diagnostic method, fast neutron radiography suffers from a number of disadvantages, the main ones being lack of sensitivity of the image-forming system and the hazard to the patient due to a large Quality Factor. Estimation of the absorbed dose given to different types of tissue is an important factor in the medical use of fast neutrons. More data are needed on the processes whereby fast neutrons impart energy to matter, particularly for neutrons above 15 MeV