Published November 14, 1962
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The origin of cholesterol in chyle demonstrated by nuclear indicator methods
Description
In order to obtain information about the mechanism of the intestinal absorption of cholesterol, rats having a lymphatic abdominal fistula are used. The animals receive either 4-14C- cholesterol subcutaneously or orally, or the 1-14C acetate. The study of the specific radio-activities of the cholesterol in chyle, in serum, in the lining, and in the intestinal contents makes it possible to define the roles played by the transfer cholesterol from the serum, by the cholesterol synthesised intestinally, and by the absorption cholesterol, in the formations of the lymph and of the chylomicrons. A new theory is proposed for the mechanism of cholesterol absorption. (author)
Availability note (English)
Available from INIS in electronic formAbstract (French)
Pour obtenir des renseignements concernant le mecanisme de l'absorption intestinale du cholesterol, on utilise des rats porteurs d'une fistule lymphatique abdominale. Les animaux recoivent soit du cholesterol 4-14C par voie sous-cutanee ou par voie orale, soit de l'acetate 1-14C. L'etude des radioactivites specifiques du cholesterol du chyle, du serum, de la paroi et du contenu intestinal permet de preciser les roles joues par le cholesterol de transfert d'origine serique, par le cholesterol de synthese intestinale et par le cholesterol d'absorption, dans la formation de la lymphe et des chylomicrons. Une theorie nouvelle concernant le mecanisme de l'absorption du cholesterol est proposee. (auteur)Files
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Additional details
Additional titles
- Original title (French)
- Origines du cholesterol du chyle mises en evidence par la methode des indicateurs nucleaires
Publishing Information
- Imprint Pagination
- 52 p.
- Report number
- CEA-R--2225
INIS
- Country of Publication
- France
- Country of Input or Organization
- France
- INIS RN
- 35044230
- Subject category
- S60: APPLIED LIFE SCIENCES; S62: RADIOLOGY AND NUCLEAR MEDICINE;
- Resource subtype / Literary indicator
- Thesis
- Descriptors DEI
- ABDOMEN; ACETATES; AMINOTRANSFERASES; BIOSYNTHESIS; BLOOD SERUM; CARBON 14; CARBON 14 COMPOUNDS; CHOLESTEROL; CHYLOMICRONS; INTESTINAL ABSORPTION; LYMPH; LYMPH NODES; RATS; TISSUE DISTRIBUTION; TRACER TECHNIQUES
- Descriptors DEC
- ABSORPTION; ANIMALS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BIOLOGICAL MATERIALS; BLOOD; BLOOD PLASMA; BODY; BODY FLUIDS; CARBON COMPOUNDS; CARBON ISOTOPES; CARBOXYLIC ACID SALTS; DISTRIBUTION; ENZYMES; EVEN-EVEN NUCLEI; HYDROXY COMPOUNDS; ISOTOPE APPLICATIONS; ISOTOPES; LABELLED COMPOUNDS; LIGHT NUCLEI; LYMPHATIC SYSTEM; MAMMALS; MATERIALS; NITROGEN TRANSFERASES; NUCLEI; ORGANIC COMPOUNDS; PROTEINS; RADIOISOTOPES; RODENTS; SORPTION; STEROIDS; STEROLS; SYNTHESIS; TRANSFERASES; UPTAKE; VERTEBRATES; YEARS LIVING RADIOISOTOPES
Optional Information
- Notes
- 88 refs.