Published January 1993 | Version v1
Journal article Metadata-only

Detection of the Epstein-Barr virus genome in the radiation-associated malignant lymphomas

Creators

  • 1. Institut Ehksperimental'noj Patologii, Onkologii i Radiobiologii, Akademii Nauk Ukrainy, Kiev (Ukraine)

Description

The genomic and ultrastructural peculiarities of malignant lymphoma cells in the patients living in the radiation unfavourable regions have been examined. The specific viral genomic sequences of EBV are revealed in the lymphoma cells in 3 of 4 patients. The described EBV-associated lymphomas are correlated with a significant decrease of natural anti tumour immunity in all the patients. The obtained data can serve as an evidence of the important role of the Epstein-Barr herpes virus in the mechanism of lymphoid cells malignant transformation

Additional details

Additional titles

Original title (Ukrainian)
Viyavlennya genomu vyirusu Epshtejna-Barr u klyitinakh radyiatsyijno asotsyijovanikh zloyakyisnikh lyimfom

Publishing Information

Journal Title
Doklady Akademii Nauk Ukrainy (1991)
Journal Issue
no.1
Journal Page Range
p. 100-104.
ISSN
0868-8044
CODEN
DAUREK

INIS

Country of Publication
Ukraine
Country of Input or Organization
Ukraine
INIS RN
25000491
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
Descriptors DEI
CHERNOBYLSK-4 REACTOR; DELAYED RADIATION EFFECTS; DISEASE RESISTANCE; DNA; ENVIRONMENTAL EXPOSURE PATHWAY; GENETIC RADIATION EFFECTS; IMMUNE SYSTEM DISEASES; IMMUNOSUPPRESSION; LYMPHOMAS; PATIENTS; REACTOR ACCIDENTS; VIRUSES
Descriptors DEC
ACCIDENTS; ANIMALS; BIOLOGICAL EFFECTS; BIOLOGICAL RADIATION EFFECTS; DISEASES; ENRICHED URANIUM REACTORS; GENETIC EFFECTS; GRAPHITE MODERATED REACTORS; LWGR TYPE REACTORS; MAMMALS; MAN; MICROORGANISMS; NEOPLASMS; NUCLEIC ACIDS; ORGANIC COMPOUNDS; PARASITES; POWER REACTORS; PRIMATES; RADIATION EFFECTS; REACTORS; THERMAL REACTORS; VERTEBRATES