Published May 2005
| Version v1
Journal article
Detoxification of blood using injectable magnetic nanospheres: A conceptual technology description
Creators
- 1. Nanoscale Engineering Group, Chemical Engineering Division, University of Chicago, Argonne National Laboratory, 9700 South Cass Avenue, Argonne, IL 60439 (United States)
- 2. Neuroscience Critical Care and Acute Stroke Program, Departments of Neurology and Neurosurgery, University of Chicago and Pritzker School of Medicine, 5841 South Maryland Ave, MC 2030, Chicago, IL 60637 (United States)
Description
We describe injectable magnetic nanospheres as a vehicle for selective detoxification of blood borne toxins. Surface receptors on the freely circulating nanospheres bind to toxins. A hand-held extracorporeal magnetic filter separates the toxin-loaded nanospheres from the clean blood, which is returned to the patient. Details of the technology concept are given and include a state-of-knowledge and research needs
Additional details
Identifiers
- DOI
- 10.1016/j.jmmm.2005.02.055;
- PII
- S0304-8853(05)00193-9;
Publishing Information
- Journal Title
- Journal of Magnetism and Magnetic Materials
- Journal Volume
- 293
- Journal Issue
- 1
- Journal Page Range
- p. 398-403
- ISSN
- 0304-8853
- CODEN
- JMMMDC
Conference
- Title
- 5. International conference on scientific and clinical applications of magnetic carriers
- Dates
- 20-22 May 2004
- Place
- Lyon (France)
INIS
- Country of Publication
- Netherlands
- Country of Input or Organization
- International Atomic Energy Agency (IAEA)
- INIS RN
- 37029326
- Subject category
- S60: APPLIED LIFE SCIENCES;
- Resource subtype / Literary indicator
- Conference
- Descriptors DEI
- BLOOD; DETOXIFICATION; MAGNETIC FILTERS; MAGNETIC MATERIALS; MICROSPHERES; NANOSTRUCTURES; RECEPTORS; SURFACES; TOXINS; VEHICLES
- Descriptors DEC
- ANTIGENS; BIOLOGICAL MATERIALS; BODY FLUIDS; FILTERS; HAZARDOUS MATERIALS; MATERIALS; MEMBRANE PROTEINS; ORGANIC COMPOUNDS; PROTEINS; TOXIC MATERIALS
Optional Information
- Copyright
- Copyright (c) 2005 Elsevier Science B.V., Amsterdam, The Netherlands, All rights reserved.