Post-processing of Monte Carlo simulations for rapid BNCT source optimization studies
Description
A great advantage of some neutron sources, such as accelerator-produced sources, is that they can be tuned to produce different spectra. Unfortunately, optimization studies are often time-consuming and difficult, as they require a lengthy Monte Carlo simulation for each source. When multiple characteristics, such as energy, angle, and spatial distribution of a neutron beam are allowed to vary, an overwhelming number of simulations may be required. Many optimization studies, therefore, suffer from a small number of datapoints, restrictive treatment conditions, or poor statistics. By scoring pertinent information from every particle tally in a Monte Carlo simulation, then applying appropriate source variable weight factors in a post-processing algorithm, a single simulation can be used to model any number of multiple sources. Through this method, the response to a new source can be modeled in minutes or seconds, rather than hours or days, allowing for the analysis of truly variable source conditions of much greater resolution than is normally possible when a new simulation must be run for each datapoint in a study. This method has been benchmarked and used to recreate optimization studies in a small fraction of the time spent in the original studies
Availability note (English)
Available from INIS in electronic form; Also available from OSTI as DE00782538; PURL: https://www.osti.gov/servlets/purl/782538-j7q4Bs/webviewable/
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Additional details
Identifiers
Publishing Information
- Imprint Pagination
- 2 p.
- Report number
- LBNL--47734
Conference
- Title
- 9. International Symposium of Neutron Capture Therapy for Cancer
- Dates
- 2-6 Oct 2000
- Place
- Osaka (Japan)
INIS
- Country of Publication
- United States
- Country of Input or Organization
- United States
- INIS RN
- 33010202
- Subject category
- S62: RADIOLOGY AND NUCLEAR MEDICINE; S99: GENERAL AND MISCELLANEOUS;
- Resource subtype / Literary indicator
- Conference
- Descriptors DEI
- COMPUTERIZED SIMULATION; MONTE CARLO METHOD; NEOPLASMS; NEUTRON CAPTURE THERAPY; NEUTRON SOURCES; OPTIMIZATION; PLANNING; RESOLUTION; SPATIAL DISTRIBUTION
- Descriptors DEC
- CALCULATION METHODS; DISEASES; DISTRIBUTION; MEDICINE; NEUTRON THERAPY; NUCLEAR MEDICINE; PARTICLE SOURCES; RADIATION SOURCES; RADIOLOGY; RADIOTHERAPY; SIMULATION; THERAPY
Optional Information
- Contract/Grant/Project number
- AC03-76SF00098
- Funding organization
- USDOE Director, Office of Science (United States)