Published September 29, 1987
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Aspects pertinent to the usefulness of a solid phase radio-immuno-sorbent assay for the detection of spermatozoa antibodies in sera of infertility patients
Description
The solid phase Radio-Immuno-Sorbent Assay (RISA) is a highly sensitive and valid test to detect 125-iodinetagged antibodies to spermatozoa that allows qualitative and quantitative evaluations of sperm-incapacitating immunglobulin Ig G in sera from patients believed to be infertile for immunological reasons. The study failed to reveal any correlations between the results of RISA and those of micro-sperm-agglutination or micro-sperm-immobilisation tests. There was a major body of evidence pointing to possible links between female isoimmunity and male autoimmunity. (TRV)
Availability note (English)
MF available from INIS under the Report Number.Abstract (German)
Der hoch sensitive und valide Festphasen-Radioimmunsorbent-Test (RIST) zum Nachweis von (mit 125Jod markierten) Spermatozoen-Antikoerpern macht qualitative und quantitative Aussagen ueber das Anti-Spermatozoen-Ig G in Seren von Patienten mit immunologischer Sterilitaet moeglich. Es wurde keine Korrelation zwischen den Befunden des RIST und den Mikrospermagglutinations- bzw. Mikrospermimmobilisationstesten gefunden. Aufgrund der Ergebnisse wird vermutet, dass weibliche Isoimmunitaet mit maennlicher Autoimmunitaet verknuepft ist. (TRV)
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Additional details
Additional titles
- Original title (German)
- Ueber die Anwendbarkeit des Festphasen-Radioimmunsorbent-Testes zum Nachweis von Spermatozoenantikoerpern in Seren von Sterilitaetspatienten
Publishing Information
- Imprint Pagination
- 47 p.
- Report number
- INIS-mf--12041
INIS
- Country of Publication
- Germany
- Country of Input or Organization
- Germany
- INIS RN
- 21019653
- Subject category
- S62: RADIOLOGY AND NUCLEAR MEDICINE;
- Resource subtype / Literary indicator
- Thesis
- Descriptors DEI
- ANTIBODIES; ANTIGEN-ANTIBODY REACTIONS; BLOOD SERUM; DIAGNOSIS; IODINE 125; MEN; PATIENTS; RADIOIMMUNOASSAY; SPERMATOZOA; STATISTICS; STERILITY; WOMEN
- Descriptors DEC
- ANIMALS; BETA DECAY RADIOISOTOPES; BIOLOGICAL MATERIALS; BLOOD; BLOOD PLASMA; BODY FLUIDS; DAYS LIVING RADIOISOTOPES; ELECTRON CAPTURE RADIOISOTOPES; FEMALES; GAMETES; GERM CELLS; IMMUNOASSAY; INTERMEDIATE MASS NUCLEI; INTERNAL CONVERSION RADIOISOTO; IODINE ISOTOPES; ISOTOPE APPLICATIONS; ISOTOPES; MALES; MAMMALS; MAN; MATERIALS; MATHEMATICS; NUCLEI; ODD-EVEN NUCLEI; PRIMATES; RADIOISOTOPES; TRACER TECHNIQUES; VERTEBRATES