PIXE analysis of Co and Fe in the serum and bone marrow of mice having acquired radio-resistance after small-dose pre-irradiation: Preliminary experiment

The death of animals occurring due to exposure to less than 10 Gy of ionizing is called bone marrow death. Radiation destroys blood-forming tissues such as bone marrow that produce blood cells. Mice acquire radio-resistance after a small dose pre-irradiation. We tried to obtain some information on the mechanism of the radio-adaptive survival response by measuring Co and other elements in bone marrow and serum of irradiated mice by PIXE. Fe increased after irradiation with 5.0 Gy in bone marrow. But the Co/Fe ratio on day 11 in bone marrow and the ratio on days 10 and 15 in serum after the irradiation was not affected by the pre-irradiation (0.5 Gy)