Published February 2011
| Version v1
Journal article
Studies on stabilities of some human chorionic gonadotropin complexes with β-emitting radionuclides
- 1. Chemical Sciences Division, Saha Institute of Nuclear Physics, 1/AF Bidhannagar, Kolkata 700064 (India)
- 2. Department of Chemistry, University of Calcutta, 92 APC Road, Kolkata 700009 (India)
- 3. Malda Town Divisional Railway Hospital, Malda 732102 (India)
Description
Human chorionic gonadotropin (hCG) is a peptide hormone, whose one of the structural subunits is identical to that of thyroid-stimulating hormone (TSH). As a consequence, the receptors of TSH also act as receptor for hCG hormone. Keeping in mind this interesting property of hCG we have studied the complex formation ability of various no-carrier-added β-emitting isotopes of 61Cu (3.3 h), 62Zn (9.2 h), 90Nb (14.60 h) and 99Mo (66.02 h) with hCG molecule. Stability of the hCG-M (M=metal ions) complexes was investigated by dialysis with respect to triple distilled water and ringer lactate solution, which has the same composition as extracellular fluid.
Availability note (English)
Available from http://dx.doi.org/10.1016/j.apradiso.2010.11.019Additional details
Identifiers
- DOI
- 10.1016/j.apradiso.2010.11.019;
- PII
- S0969-8043(10)00448-3;
Publishing Information
- Journal Title
- Applied Radiation and Isotopes
- Journal Volume
- 69
- Journal Issue
- 2
- Journal Page Range
- p. 316-319
- ISSN
- 0969-8043
- CODEN
- ARISEF
INIS
- Country of Publication
- United Kingdom
- Country of Input or Organization
- International Atomic Energy Agency (IAEA)
- INIS RN
- 42077041
- Subject category
- S07: ISOTOPES AND RADIATION SOURCES; S62: RADIOLOGY AND NUCLEAR MEDICINE;
- Descriptors DEI
- COMPLEXES; COPPER 61; DIALYSIS; HCG; LACTATES; MOLYBDENUM 99; NIOBIUM 90; RECEPTORS; TSH; ZINC 62
- Descriptors DEC
- BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BETA-PLUS DECAY RADIOISOTOPES; CARBOXYLIC ACID SALTS; COPPER ISOTOPES; DAYS LIVING RADIOISOTOPES; ELECTRON CAPTURE RADIOISOTOPES; EVEN-EVEN NUCLEI; EVEN-ODD NUCLEI; GONADOTROPINS; HORMONES; HOURS LIVING RADIOISOTOPES; INTERMEDIATE MASS NUCLEI; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; MEMBRANE PROTEINS; MOLYBDENUM ISOTOPES; NIOBIUM ISOTOPES; NUCLEI; ODD-EVEN NUCLEI; ODD-ODD NUCLEI; ORGANIC COMPOUNDS; PEPTIDE HORMONES; PITUITARY HORMONES; PROTEINS; RADIOISOTOPES; SECONDS LIVING RADIOISOTOPES; SEPARATION PROCESSES; ZINC ISOTOPES
Optional Information
- Copyright
- Copyright (c) 2010 Elsevier Science B.V., Amsterdam, The Netherlands, All rights reserved.