Published June 1987
| Version v1
Report
Coordination chemistry of the Pb-212/Bi-212 nuclear transformation; alpha emitting radiopharmaceuticals
Description
This progress report briefly highlights the areas of research activity for FY85. Radiochemical procedures to produce Bi-205/206 tracer for chemical studies of the Pb-212 to Bi-212 nuclear transformation are reviewed. The developmental work on a Pb-212/Bi-212 generator system suitable for both chemical studies of recoil synthesis of Pb-212 Bi-212 compounds is discussed. Synthesis of candidate ligands that complex both lead and bismuth is discussed. Bismuth subcellular distribution and initial in vivo protein binding results are discussed
Additional details
Publishing Information
- Imprint Title
- Annual report of the Energy-Related Health Research Program of the University of California, Davis, 1985
- Journal Page Range
- p. 124-129.
- Report number
- UCD--472-131
INIS
- Country of Publication
- United States
- Country of Input or Organization
- United States
- INIS RN
- 19044044
- Subject category
- S38: RADIATION CHEMISTRY, RADIOCHEMISTRY AND NUCLEAR CHEMISTRY; S62: RADIOLOGY AND NUCLEAR MEDICINE; S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Descriptors DEI
- BISMUTH 205; BISMUTH 206; BISMUTH 212; CHEMICAL PREPARATION; LEAD 212; RADIOCHEMISTRY; RADIONUCLIDE KINETICS; RADIOPHARMACEUTICALS; SUBCELLULAR DISTRIBUTION
- Descriptors DEC
- ALPHA DECAY RADIOISOTOPES; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BETA-PLUS DECAY RADIOISOTOPES; BISMUTH ISOTOPES; CHEMISTRY; DAYS LIVING RADIOISOTOPES; DISTRIBUTION; DRUGS; ELECTRON CAPTURE RADIOISOTOPES; EVEN-EVEN NUCLEI; HEAVY NUCLEI; HOURS LIVING RADIOISOTOPES; ISOTOPES; KINETICS; LABELLED COMPOUNDS; LEAD ISOTOPES; MATERIALS; MINUTES LIVING RADIOISOTOPES; NUCLEI; ODD-EVEN NUCLEI; ODD-ODD NUCLEI; RADIOACTIVE MATERIALS; RADIOISOTOPES; SYNTHESIS