Comparison of hemodynamic changes after intubation with macintosh and mccoy laryngoscopes–a randomised controlled trial

Objective: To compare hemodynamic changes (systolic blood pressure and pulse) after intubation with Macintosh and McCoy laryngoscopes. Study Design: Randomised control trial (Clinicaltrials.gov: NCT05133375) Place and Duration of Study: Combined Military Hospital, Jhelum Pakistan, from Apr to Oct 2021. Methodology: A group of 272 patients reporting to the operation theatre were selected and divided into Group-A and B using the lottery method. All patients had ASA class I and II score and Mallampati score of I and II with no comorbid conditions. Macintosh laryngoscope was used in Group-A, and McCoy laryngoscope was used in Group-B. Before intubation, systolic blood pressure and pulse were measured, as well as 30 seconds, 2 minutes, and 3 minutes following intubation. In addition, a comparison of both groups regarding systolic blood pressure and pulse was made. Results: The patients in the study had a mean age of 34.93±9.66 years. The increase (20%) in heart rate was significantly higher in the Macintosh-Group 23(16.9%), than in the McCoy-Group 8(4.4%), (p=0.001), and the 20% increase in systolic pressure was also found to be significantly higher in the Macintosh-Group as compared to the McCoy-Group, 26(19.1%) versus 8(6.6%), (p=0.002). Conclusion: According to our research, using the McCoy blade is a safer mode of intubation in terms of the hemodynamic response. (author)