Published August 2017 | Version v1
Journal article Metadata-only

Dose–volume toxicity modeling for de-intensified chemo-radiation therapy for HPV-positive oropharynx cancer

Creators

  • 1. Department of Radiation Oncology, University of North Carolina, Chapel Hill (United States)
  • 2. Shands Cancer Center, University of Florida Hospitals, Gainesville (United States)
  • 3. Department of Radiation Oncology, University of Florida Hospitals, Gainesville (United States)
  • 4. Lineberger Comprehensive Cancer Center, University of North Carolina Hospitals, Chapel Hill (United States)

Description

Background and purpose: The aim is to determine the radiobiological parameters of four popular normal tissue complication probability (NTCP) models that describe the dose–response relations of salivary glands and pharyngeal constrictors to the severity of patient reported xerostomia and dysphagia, respectively 6 and 12 months post chemo-radiotherapy, furthermore, to evaluate the goodness-of-fit of the NTCP models for different combinations of glands and constrictors.

Availability note (English)

Available from http://dx.doi.org/10.1016/j.radonc.2017.06.020

Additional details

Identifiers

DOI
10.1016/j.radonc.2017.06.020;
PII
S0167814017304310;

Publishing Information

Journal Title
Radiotherapy and Oncology
Journal Volume
124
Journal Issue
2
Journal Page Range
p. 240-247
ISSN
0167-8140
CODEN
RAONDT

INIS

Country of Publication
Ireland
Country of Input or Organization
International Atomic Energy Agency (IAEA)
INIS RN
50081019
Subject category
S62: RADIOLOGY AND NUCLEAR MEDICINE;
Descriptors DEI
NEOPLASMS; PATIENTS; RADIATION DOSES; RADIOTHERAPY; SALIVARY GLANDS; TOXICITY
Descriptors DEC
BODY; DISEASES; DOSES; GLANDS; MEDICINE; NUCLEAR MEDICINE; ORGANS; RADIOLOGY; THERAPY

Optional Information

Copyright
Copyright (c) 2017 Elsevier Science B.V., Amsterdam, The Netherlands, All rights reserved.