Hydroxyapatite Based 99Mo-99mTc and 188W-188Re Generator Systems

This paper describes studies evaluating the use of hydroxyapatite as the adsorbent material for both 99Mo-99mTc and 188W-188Re generator systems. Hydroxyapatite is an insoluble solid with anion exchange properties. A study of the sorption behaviour of 99Mo, 99mTc, 188W and 188Re on hydroxyapatite in NaCl medium was evaluated by batch experiments. The results demonstrated that while 99Mo, 99mTc and 188Re are not adsorbed by the hydroxyapatite in NaCl solutions (Kd <5), 188W is strongly adsorbed (Kd >500). On the basis of these measurements, hydroxyapatite 188W-188Re generator systems were then constructed and eluted in NaCl solutions. The hydroxyapatite based 188W-188Re generator performances are presented