Published March 2015 | Version v1
Journal article Metadata-only

Research progress and prediction on pleiotropic protein PprA from Deinococcus radiodurans

Creators

  • 1. Department of Radiation Medicine, School of Public Health, University of South China, Hengyang (China)
  • 2. Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study, Hengyang (China)
  • 3. Department of Biochemistry and Molecular Biology, University of South China, Hengyang (China)

Description

Deinococcus radiodurans (DR) is a model organism to study radiation resistance. PprA protein (pleiotropic protein promoting DNA repair) is a unique, pleiotropic protein promoting DNA repair in DR. This article reviewed its possible function in DNA damage repairing, maintenance of genome stability and other aspects. Furthermore, we analyze its domain of pprA genes and by bioinformatics and predict interaction protein with PprA protein, in order to predict its function and understand the mechanisms and pathways it plays. (authors)

Additional details

Identifiers

DOI
10.3760/cma.j.issn.1673-4114.2015.02.010;

Publishing Information

Journal Title
International Journal of Radiation Medicine and Nuclear Medicine
Journal Volume
39
Journal Issue
2
Journal Page Range
p. 149-153
ISSN
1673-4114

INIS

Country of Publication
China
Country of Input or Organization
China
INIS RN
51068326
Subject category
S60: APPLIED LIFE SCIENCES;
Descriptors DEI
DNA DAMAGES; DNA REPAIR; GENES; IONIZING RADIATIONS; MICROCOCCUS RADIODURANS; PROTEINS; STABILITY
Descriptors DEC
BACTERIA; BIOLOGICAL RECOVERY; BIOLOGICAL REPAIR; MICROCOCCUS; MICROORGANISMS; ORGANIC COMPOUNDS; RADIATIONS; REPAIR

Optional Information

Notes
2 figs., 29 refs.; http://dx.doi.org/10.3760/cma.j.issn.1673-4114.2015.02.010