Published 1982 | Version v1
Miscellaneous

Application of a high-pressure liquid chromatograph for separation and identification of radioactive labelled compounds

  • 1. Institut yadernoj biologii i radiokhimii ChSAN, Prague, Czechoclovakia

Description

A liquid chromatograph was constructed in the Institute of Nuclear Biology and Radiochemisctry Czech.Acad.Sci. from components and parts of Czechoslovak production. It is used for separation of radioactive labelled compounds. The conditions have been determined for separation of tritium-labelled derivatives of rifampicin. A method has been developed also for separation of iodine derivatives of estradiol. Individual iodine derivatives were identified. Subsequently, the iodination of estradiol was carried out with carrier-free Na125I and individual 125I derivatives were separated from reaction mixture by HPLC; for this purpose the instrument was supplemented with a flow cell for the detection of 125I

Additional details

Additional titles

Original title (Russian)
Использование жидкостного хроматограпха, работающего при высоких давлениях, для сепарации и анализа радиоактивно меченных соединений

Publishing Information

Imprint Title
Radioisotope-labelled organic compounds. Part 2
Journal Page Range
p. 234-242.
Report number
INIS-mf--10548

Conference

Title
Radioisotope-labelled organic compounds.
Dates
8-11 Dec 1981.
Place
Leningrad (USSR).

Optional Information

Notes
5 figs. Imprint:Organicheskie soedineniya, mechennye radioaktivnymi izotopami.;Materialy 2 Simpoziuma stran-chlenov SEhV, Leningrad, 8-11 dekabrya 1981 g. Chast'2.