Published January 2012 | Version v1
Journal article

Effect of quercetin and 17-AAG on radiosensitivity of rat peripheral blood lymphocyte

  • 1. School of Radiation Medicine and Public Health, Medical College of Soochow University, Jiangsu Provincial Key Laboratory of Radiation Medicine and Protection, Suzhou (China)

Description

To investigate the effect of quercetin and 17-AAG on proliferation and on radiosensitivity of blood lymphocyte cells. CCK-8 assay is performed to evaluate the cytotoxicity of Quercetin on proliferation of blood lymphocyte cells. CCK-8 assay employed to observe its effects on the radiosensitivity of the cells quantified by calculating the sensitive enhancement ratio (SER). CCK-8 results showed that the inhibition of Quercetin on the cells was the dose-dependent and time-dependent, and the results of assay showed the inhibition of 17-AAG on blood lymphocyte cells was the dose-dependent and time-dependent. The study showed that Quercetin and 17-AAG have no effect on the radiosensitivity of the blood lymphocyte cells. (authors)

Additional details

Publishing Information

Journal Title
Radiation Protection (Taiyuan)
Journal Volume
32
Journal Issue
1
Journal Page Range
p. 28-33
ISSN
1000-8187

Optional Information

Notes
5 figs., 20 refs.