Preparation and characterization of new copper nickel vanadium oxide pyrochlore via solid state reaction, and its application in electrochemical sensing of acetaminophen

Highlights: • Successfully synthesize of Copper Nickel Vanadium oxide CuNiV₂O₇ via solid state method under temperature programming. • Utilization of as synthesized pyrochlore for modification of the sol-gel electrode bulk (CuNiV₂O₇/SGE). • Development of an electrochemical sensor to measure acetaminophen (AC). • Application of the CuNiV₂O₇/SGE for determination of AC in pharmaceutical tablets and urine samples with a good accuracy. Copper Nickel Vanadium oxide CuNiV₂O₇, was successfully synthesized via solid state method under temperature programming. The triclinic pattern of the P1̅ crystalline phase formation was verified by FT-IR spectral analysis and XRD. Morphological analysis was performed using EDX analysis, elemental mapping and FE-SEM. DRS-UV-visible and photoluminescence (PL) spectroscopy were used for obtaining optical characteristics of the CuNiV₂O₇ nanoparticles. As synthesized pyrochlore was utilized for modification of the working electrode and consequently development of an electrochemical sensor to measure acetaminophen (AC). Optimizing of this new application was controlled by various experimental variables which affect the electrochemical performance of the Copper Nickel Vanadium oxide CuNiV₂O₇ modified sol-gel electrode (CuNiV₂O₇/SGE) toward AC determination. The developed CuNiV₂O₇ modified sol-gel electrode was successfully utilized for determination of AC in real samples, including pharmaceutical tablets and urine samples with a good accuracy which confirmed by recovery values.