Published December 10, 1986 | Version v1
Journal article Metadata-only

Photometric determination of aminothiol impurities in Gammafos

Creators

  • 1. A. N. Nesmeyanov Institute of Heteroorganic Compounds, Moscow, USSR

Description

A procedure was developed for photometric determination of γ-amino-propylaminoethyl-thiol impurities (to 2%) in S-[N-(γ-aminopropyl)-β-aminoethyl]thiophosphate (Gammafos) with Ellman's reagent. A symmetric disulfide does not interfere in the determination of the thiol. When the analysis is carried out rapidly (1 min, pH 7.0), the effect of Gammafos on the determination of the thiol is eliminated. The disulfide is determined indirectly according to the thiol concentration after complete hydrolysis of Gammafos

Additional details

Publishing Information

Journal Title
J. Anal. Chem. USSR (Engl. Transl.)
Journal Volume
41
Journal Issue
6
Series
J. Anal. Chem. USSR (Engl. Transl.).
Journal Page Range
863-865
ISSN
0021-8766
CODEN
JACUA

INIS

Country of Publication
United States
Country of Input or Organization
United States
INIS RN
19040332
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS; S37: INORGANIC, ORGANIC, PHYSICAL AND ANALYTICAL CHEMISTRY;
Resource subtype / Literary indicator
Translation
Descriptors DEI
AMINES; BENZOIC ACID; BIOLOGICAL RADIATION EFFECTS; DISULFIDES; GAMMAPHOS; IMPURITIES; MATERIALS TESTING; NITRO COMPOUNDS; QUANTITATIVE CHEMICAL ANALYSIS; RADIATION PROTECTION; RADIOTHERAPY; REAGENTS; SPECTROPHOTOMETRY; THIOLS; TISSUES
Descriptors DEC
BIOLOGICAL EFFECTS; BODY; CARBOXYLIC ACIDS; CHEMICAL ANALYSIS; DRUGS; ESTERS; MEDICINE; MONOCARBOXYLIC ACIDS; ORGANIC ACIDS; ORGANIC COMPOUNDS; ORGANIC NITROGEN COMPOUNDS; ORGANIC SULFUR COMPOUNDS; RADIATION EFFECTS; RADIOPROTECTIVE SUBSTANCES; RESPONSE MODIFYING FACTORS; TESTING; THERAPY; THIOPHOSPHORIC ACID ESTERS

Optional Information

Notes
Translated from Zh. Anal. Khim.; 41: No. 6, 1101-1104(Jun 1986).