Published March 1988
| Version v1
Journal article
Alterations in the system of cyclic nucleotides in irradiated organism tissues
Description
It has been shown that the content of cAMP in the rat thymus, spleen, and liver 1 and 3 after γ-irradiation with 7.5 Gy decreases, and that of cGMP increase. Analogous dynamics has been revealed when studying adenylate cyclase and guanylate cyclase activities. The activity of cAMP and cGMP phosphodiesterases increased during the first period of study but subsequently it showed no distinction from the initial data level. The revealed postradiation changes in the content of cyclic nucleotides seem to be basically caused by the cyclases activity alterations
Additional details
Additional titles
- Original title (Russian)
- Изменения в системе циклических нуклеотидов в тканях облученного организма
Publishing Information
- Journal Title
- Radiobiologiya
- Journal Volume
- 28
- Journal Issue
- 2
- Series
- Radiobiologiya.
- Journal Page Range
- 201-204
- ISSN
- 0033-8192
- CODEN
- RADOA
INIS
- Country of Publication
- Russian Federation
- Country of Input or Organization
- USSR
- INIS RN
- 19099517
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Descriptors DEI
- BIOLOGICAL RADIATION EFFECTS; CESIUM 137; CHOLINE; DNA; ENZYME ACTIVITY; ENZYMES; LIVER; MALES; NUCLEOTIDES; RADIOIMMUNOASSAY; RATS; SPLEEN; THYMUS; TIME DEPENDENCE
- Descriptors DEC
- ALCOHOLS; AMINES; ANIMALS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BIOLOGICAL EFFECTS; BODY; CESIUM ISOTOPES; DIGESTIVE SYSTEM; DRUGS; GLANDS; HYDROXY COMPOUNDS; IMMUNOASSAY; INTERMEDIATE MASS NUCLEI; ISOTOPE APPLICATIONS; ISOTOPES; LIPOTROPIC FACTORS; LYMPHATIC SYSTEM; MAMMALS; NUCLEI; NUCLEIC ACIDS; ODD-EVEN NUCLEI; ORGANIC COMPOUNDS; ORGANS; QUATERNARY COMPOUNDS; RADIATION EFFECTS; RADIOISOTOPES; RODENTS; TRACER TECHNIQUES; VERTEBRATES; YEARS LIVING RADIOISOTOPES