Published November 1989 | Version v1
Journal article Metadata-only

Influence of brachytherapy (192Ir afterloading) on cell-mediated immune reactions in patients with stage I endometrial cancer

Creators

  • 1. Vienna Univ. Medical School (Austria)

Description

The influence of radiation therapy on cell-mediated immune reactions in cancer patients seems to depend on source, dose, and area of irradiation, as well as on the variables reflected by the patient population investigated. In the present study we demonstrated that brachytherapy (192Ir afterloading), applied to patients with inoperable stage I endometrial cancer, has no immediate or sustained effect on lymphocyte function. Both lymphocyte mitogen response and natural killer cell (NK) activity are not significantly changed in terms of baseline values compared with test results during and after therapy. Brachytherapy, as used in this study, has no influence on cell-mediated immunity in patients with endometrial cancer stage I

Additional details

Publishing Information

Journal Title
Gynecologic Oncology
Journal Volume
35
Journal Issue
2
Series
Gynecol. Oncol.
Journal Page Range
164-169
ISSN
0090-8258
CODEN
GYNOA

INIS

Country of Publication
United States
Country of Input or Organization
United States
INIS RN
21031938
Subject category
S62: RADIOLOGY AND NUCLEAR MEDICINE;
Descriptors DEI
AFTERLOADING; BIOLOGICAL FUNCTIONS; IMMUNE REACTIONS; IMMUNITY; IRIDIUM 192; LYMPHOCYTES; NEOPLASMS; PATIENTS; RADIOTHERAPY; UTERUS
Descriptors DEC
ANIMAL CELLS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BIOLOGICAL MATERIALS; BLOOD; BLOOD CELLS; BODY; BODY FLUIDS; CONNECTIVE TISSUE CELLS; DAYS LIVING RADIOISOTOPES; DISEASES; ELECTRON CAPTURE RADIOISOTOPES; FEMALE GENITALS; HEAVY NUCLEI; INTERNAL CONVERSION RADIOISOTO; IRIDIUM ISOTOPES; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; LEUKOCYTES; MATERIALS; MEDICINE; MINUTES LIVING RADIOISOTOPES; NUCLEI; ODD-ODD NUCLEI; ORGANS; RADIOISOTOPES; SOMATIC CELLS; THERAPY; YEARS LIVING RADIOISOTOPES