Published July 1989 | Version v1
Journal article Metadata-only

Use of nude mice in experimental neutron capture therapy with 10B-BPA

Creators

  • 1. Tokai Univ., Kanagawa-ken (Japan)

Description

Mouse B16 melanoma allografts in nude mice were successfully treated by thermal neutron irradiation after IP injection of 10B-paraboronophenylalanine hydrochloride. The tumor growth was significantly suppressed for 4 weeks after irradiation, compared with animals given neutron irradiation alone. Tumor-bearing nude mice were shown to be useful for evaluating the treatment for melanoma

Additional details

Publishing Information

Journal Title
Pigment Cell Research
Journal Volume
2
Journal Issue
4
Series
Pigment Cell Res.
Journal Page Range
343-344
ISSN
0893-5785
CODEN
PCREE

INIS

Country of Publication
United States
Country of Input or Organization
United States
INIS RN
21028302
Subject category
S62: RADIOLOGY AND NUCLEAR MEDICINE;
Descriptors DEI
BORON COMPOUNDS; BORON 10; EFFICIENCY; EXPERIMENTAL NEOPLASMS; INTRAPERITONEAL INJECTION; MELANOMAS; MICE; NEUTRON CAPTURE THERAPY; PHENYLALANINE
Descriptors DEC
AMINO ACIDS; ANIMALS; AROMATICS; BORON ISOTOPES; CARBOXYLIC ACIDS; DISEASES; INJECTION; INTAKE; ISOTOPES; LIGHT NUCLEI; MAMMALS; MEDICINE; NEOPLASMS; NEUTRON THERAPY; NUCLEI; ODD-ODD NUCLEI; ORGANIC ACIDS; ORGANIC COMPOUNDS; RADIOTHERAPY; RODENTS; STABLE ISOTOPES; THERAPY; VERTEBRATES